Newly discovered signaling pathway could impact a variety of autoinflammatory diseases

Researchers from Virginia Commonwealth University Massey Cancer Center have discovered a new signaling pathway in sterile inflammation that could impact the treatment of diseases such as cancer, multiple sclerosis and rheumatoid arthritis. Their findings offer insight into the role that activation of interferon-regulatory factor 1, a protein that functions as a transcriptional activator of a variety of target genes, plays in the production of chemokines and the recruitment of mononuclear cells t...

Fuente : http://www.eurekalert.org/pub_releases/2014-02/vcu...