New genome-editing platform significantly increases accuracy of CRISPR-based systems

A next-generation genome editing system substantially decreases the risk of producing unwanted, off-target gene mutations. Researchers report a new CRISPR-based RNA-guided nuclease technology that uses two guide RNAs, significantly reducing the chance of cutting through DNA strands at mismatched sites.

Fuente : http://feeds.sciencedaily.com/~r/sciencedaily/~3/e...